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Table 2 Ferroptosis inducers

From: Novel insights on targeting ferroptosis in cancer therapy

Category Molecule Target
SystemXc Inhibition Erastin SystemXc/VDAC/TFR1
SAS SystemXc
SRF SystemXc
GPX4 Inhibition RSL3/5 GPX4/VDAC
FINs GPX4
FINO2 GPX4
DPIs GPX4
Altretamine GPX4
Withaferin A GPX4
Others classes GLU Cystine
Iron carrier Iron
BSO GSH
DPI2 GSH
Cisplatin GSH
Artemisinin and derivative Iron
Nanoparticle inducers