A radiomics-based model on non-contrast CT for predicting cirrhosis: make the most of image data

Biomarker Research

Table 1 Baseline characteristics

Parameter	Training (n = 144)	Validation (n = 150)	P value
Sex			.88
No. of men	117 (81.3)	120 (80.0)
No. of women	27 (18.7)	30 (20.0)
Age			.49
< 60 (years)	68 (47.2)	77 (51.3)
≥ 60 (years)	76 (52.8)	73 (48.7)
CT-reported cirrhosis			.81
Cirrhosis-negative	98 (68.1)	100 (66.7)
Cirrhosis-positive	46 (31.9)	50 (33.3)
Laboratory findings^a
AST (IU/mL)	31.6 (23.5–48.2)	29.3 (21.1–38.5)	.13
ALT (IU/mL)	31.2 (22.0–50.0)	26.9 (19.6–39.6)	.07
GGT (IU/mL)	53.5 (32.0–111.4)	54.9 (29.5–91.2)	.26
Total bilirubin (ng/mL)	13.5 (9.2–18.5)	12.9 (10.0–17.8)	.16
Platelet count (10⁹/L)	141.5 (91.8–182.3)	138.5 (100.5–188.3)	.70
INR	1.04 (0.98–1.11)	1.04 (0.98–1.11)	.31
APRI	0.63 (0.41–0.98)	0.53 (0.33–0.91)	.16
FIB-4	2.65 (1.70–4.14)	2.30 (1.62–3.76)	.21
Histologic grade			.59
F0	18 (12.5)	14 (9.3)	.46
F1	24 (16.7)	32 (21.3)	.37
F2	13 (9.0)	18 (12.0)	.45
F3	26 (18.1)	29 (19.3)	.88
F4	63 (43.8)	57 (38.0)	.34

Note. —Except where indicated, data are numbers of patients, with percentages in parentheses. ALT alanine aminotransferase, APRI aspartate aminotransferase-to-platelet ratio, AST aspartate aminotransferase, FIB-4 fibrosis-4 index, GGT γ-glutamyl transferase, INR international normalized ratio
^aData are medians, with interquartile range in parentheses

ISSN: 2050-7771