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Table 3 Summary results of the meta-analysis of mean values of each Biomarker in non-survivor and survivor cases

From: A meta-analysis of potential biomarkers associated with severity of coronavirus disease 2019 (COVID-19)

Anomalies SMD (95% CI) P-value Heterogeneity
I2 (%)
Number of studies Sample size for Non-survivor Sample size survivor
Inflammation
 IL-6 1.23(0.77;1.68) < 0.001 61 2 98 177
Blood routine
 Lymphocytes count −0.67(−1.18; −0.17) 0.009 75 3 130 197
 White Blood Cells 0.89(0.04; 1.75) 0.04 90 2 98 177
Biochemestry
 Creatinemia −0.09(−0.46;0.27) 0.62 12 2 76 60
 Total bilirubin 0.55(0.20;0.89) 0.002 0 2 76 60
 LDH 1.48(0.57;2.40) 0.002 90 2 98 170
 Ferritin 0.76(−0.33;1.90) 0.18 93 2 90 122
Blood clothing
 PT 0.30(−0.14;0.75) 0.18 68 3 130 188
  1. SMD Standardized mean difference; IL-6 interleukin-6; LDH Lactate dehydrogenese; PT prothrombin time; CD3+ T CD3+ positif T lymphocytes