Table 1 Clinical characteristics of patients grouped by POD12
Characteristics | POD12 (n = 49) | Non-POD12 (n = 96) | Univariate p-value | Multivariate p-value |
|---|---|---|---|---|
Gender | ||||
 Male, n (%) | 25 (51.0) | 51 (53.1) | 0.810 |  |
IPI factors | ||||
 Age > 60 years, n (%) | 17 (34.7) | 23 (24.0) | 0.171 |  |
 LDH level > normal, n (%) | 32 (65.3) | 35 (36.5) | 0.001 | 0.018 |
 Stage III or IV, n (%) | 35 (71.4) | 49 (51.0) | 0.019 | 0.105 |
 ECOG>1, n (%) | 10 (20.4) | 9 (9.4) | 0.063 |  |
 Extranodal involvement > 1 site, n (%) | 15 (30.6) | 18 (18.8) | 0.107 |  |
IPI score | ||||
19 (38.8) | 19 (19.8) | 0.014 | Â | |
Co-expression MYC and BCL2 | ||||
 Yes, n (%) | 18 (36.7) | 13 (13.5) | 0.001 | 0.096 |
COO | ||||
 Non-GCB, n (%) | 22 (44.9) | 46 (47.9) | 0.901 |  |
Positive p53 protein | ||||
 Yes, n (%) | 14 (28.6) | 18 (18.8) | 0.127 |  |
Gene mutations | ||||
 PIM1, n (%) | 19 (38.8) | 17 (17.7) | 0.005 | 0.026 |
 CD79B, n (%) | 21 (42.9) | 9 (9.4) | 0.000 | 0.001 |