Fig. 3

Concordance of the ctDNA assessment with the tissue NGS test. a The consistent gene mutation spectrum and mutation allele frequency detected in the plasma ctDNA and tumor tissue of the patients. b Venn diagram summarizing the detailed mutations discovered in both plasma ctDNA (gray) and tumor DNA (blue). c For each patient, the fraction of tumor biopsy-confirmed mutations that were detected in plasma ctDNA is shown. The gray portion of the bar marks the part of the tumor biopsy-confirmed mutation that was not found in the plasma ctDNA