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Table 1 HNSCC Patient Characteristics

From: A preliminary analysis of interleukin-1 ligands as potential predictive biomarkers of response to cetuximab

Patient characteristics

cetuximab

(n = 34)

% (n)

no cetuximab

(n = 130)

% (n)

p value

Male

71% (24)

83% (108)

p = 0.10

Female

29% (10)

17% (22)

Mean age [range]

58.8 [35–82]

56.3 [19–80]

p = 0.22

Stage at diagnosis

 I, II

12% (4)

9% (12)

p = 0.67

 III, IV

88% (30)

90% (117)

 Unknown

0% (0)

1% (1)

HPV status

 Positive

15% (5)

18% (24)

p = 0.85

 Negative

26% (9)

26% (34)

 Unknown

59% (20)

52% (70)

Relapsed

 Yes

53% (18)

31% (40)

p = 0.043

 No

35% (12)

58% (75)

 Unknown

12% (4)

12% (15)

Received radiation therapy

 Yes

74% (25)

77% (100)

p = 0.92

 No

12% (4)

10% (13)

 Unknown

15% (5)

13% (17)

Treatment best response

 Complete response

26% (9)

42% (55)

p = 0.004

 Partial response

3% (1)

2% (3)

 Stable disease

3% (1)

1% (1)

 Progressive disease

21% (7)

3% (4)

 Unknown

47% (16)

53% (69)