Skip to main content

Advertisement

Table 3 Association between cancer and CpG-based estimates of blood cells and PC1

From: Longitudinal study of leukocyte DNA methylation and biomarkers for cancer risk in older adults

  Comparison between baseline and year 61
Baseline Year 6 p (baseline vs 6)
CD8T 0.07 ± 0.06 0.02 ± 0.02 0.006
Gran 0.46 ± 0.14 0.57 ± 0.14 0.02
PC1 −7.31 ± 15.7 8.51 ± 13.41 0.004
  Baseline (cancer yes vs. no) Year 6 (cancer yes vs. no)
Cancer No Yes p No Yes p
CD8T 0.08 ± 0.07 0.04 ± 0.02 0.16 0.03 ± 0.02 0.003 ± 0.005 0.02
Gran 0.43 ± 0.14 0.52 ± 0.12 0.17 0.52 ± 0.14 0.66 ± 0.09 0.04
PC1 −12.19 ± 13.73 2.45 ± 15.87 0.06 2.13 ± 10.99 19.14 ± 10.23 0.008
  1. 1Excludes Person 13 and data from Year 2
  2. CD8T: CD8+ T-cells; Gran: granulocytes; PC1: principal component 1