Table 3 Association between cancer and CpG-based estimates of blood cells and PC1
From: Longitudinal study of leukocyte DNA methylation and biomarkers for cancer risk in older adults
| Â | Comparison between baseline and year 61 | |||||
Baseline | Year 6 | p (baseline vs 6) | ||||
CD8T | 0.07 ± 0.06 | 0.02 ± 0.02 | 0.006 | |||
Gran | 0.46 ± 0.14 | 0.57 ± 0.14 | 0.02 | |||
PC1 | −7.31 ± 15.7 | 8.51 ± 13.41 | 0.004 | |||
| Â | Baseline (cancer yes vs. no) | Year 6 (cancer yes vs. no) | ||||
Cancer | No | Yes | p | No | Yes | p |
CD8T | 0.08 ± 0.07 | 0.04 ± 0.02 | 0.16 | 0.03 ± 0.02 | 0.003 ± 0.005 | 0.02 |
Gran | 0.43 ± 0.14 | 0.52 ± 0.12 | 0.17 | 0.52 ± 0.14 | 0.66 ± 0.09 | 0.04 |
PC1 | −12.19 ± 13.73 | 2.45 ± 15.87 | 0.06 | 2.13 ± 10.99 | 19.14 ± 10.23 | 0.008 |