Fig. 2
From: Longitudinal study of leukocyte DNA methylation and biomarkers for cancer risk in older adults
Epigenome-wide association plot. The Manhattan plot shows the association between the CpGs and cancer at Year 6. The x-axis represents the chromosomal locations, and each point depicts a CpG probe. The y-axis is the –log10(p-value) of differential methylation between those who received cancer diagnosis vs. those who remained cancer-free. The red horizontal line indicates the genome-wide significant threshold (p-value ≤5 × 10− 8) and the blue horizontal line indicates the suggestive threshold (p-value ≤10− 5)