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Fig. 12 | Biomarker Research

Fig. 12

From: Overexpression and cytoplasmic localization of caspase-6 is associated with lamin A degradation in set of ovarian cancers

Fig. 12

Immunoblot showing caspase-6 downregulation with siRNA. Primary human ovarian surface epithelial cells (HOSE), A2780 and OVCAR5 cell lines were transfected with siRNA for 72 h before cell lysates were collected for western blot analysis. HOSE cells displayed prominent levels of lamin A/C and low level of caspase-6 expression in contrast to cancer cell lines A2780 and OVCAR5. Caspase-6 downregulation was observed in A2780 and OVCAR5 cell lines but no effect was observed on lamin A/C expression

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