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Table 2 Overall survival and clinicopathological variables in 85 patients with PDAC

From: Investigation of HNF-1B as a diagnostic biomarker for pancreatic ductal adenocarcinoma

Variables

Hazard ratio (95% CI)

p-value

Univariate analysis

 Age (< 65 vs ≥65)

0.98 (0.59–1.62)

.94

 Gender (male vs. female)

1.13 (0.68–1.88)

.65

 Tumor size (<  2 cm vs. ≥ 2 cm)

2.11 (1.07–4.16)

.03

 Stage (I/II vs. III/IV)

0.74 (0.44–1.26)

.28

 Grade (low vs. high)

1.84 (1.11–3.05)

.02

 PNI

1.18 (0.70–2.01)

.54

 LVI

1.46 (0.90–2.40)

.13

 LN metastasis

1.31 (0.77–2.21)

.32

 HNF-1B (negative vs. positive)

1.34 (0.70–2.57)

.38

 No neoadjuvant

1.14 (0.41–1.14)

.80

Multivariate analysis

 Tumor size (<  2 cm vs. ≥ 2 cm)

2.10 (1.06–4.16)

.03

 Grade (low vs. high)

1.83 (1.10–3.06)

.02

  1. Abbreviations: PDAC, pancreatic ductal adenocarcinoma; VS, versus;
  2. SD standard deviation, LVI lymphovascular invasion;
  3. LN lymph node, PNI perineural invasion
  4. Bold: Statistically significant