Table 1 Clinical characteristics of participants included in the biomarker analyses
|  | Total (n = 160) | Cases (n = 79) | Controls (n = 81) | p value |
|---|---|---|---|---|
Age in years, mean (SD) | 25.4 (± 6.0) | 25.2 (± 6.2) | 25.7 (± 5.8) | 0.560 |
Preeclampsia | 0 | 0 | 0 | – |
Hemoglobin at delivery in g/dL mean (SD) | 12.0 (1.5) | 11.9 (1.6) | 12.1 (1.4) | 0.527 |
Gravidity | ||||
 Primigravidae % (n) | 22.5 (36) | 25.3 (20) | 19.8 (16) | 0.371 |
 Secundigravidae % (n) | 17.5 (28) | 16.5 (13) | 18.5 (15) | 0.784 |
 Multigravidae % (n) | 60 (96) | 58.2 (46) | 61.7 (50) | 0.595 |
Infected at first visit | ||||
 By microscopy % (n) | 31.3 (50/160) | 30.4 (24/79) | 32.1 (26/81) | 0.798 |
 By real-time PCR % (n) | 47.8 (76/159) | 48.7 (38/78) | 46.9 (38/81) | 0.799 |
Infected at delivery | ||||
 By microscopy, % (n) | 22.5 (36/160) | 43.0 (34/79) | 2.5 (2/81) | <0.001 |
 By placental biopsy, % (n) | 8.2 (11/134) | 11.9 (8/67) | 4.5 (3/67) | 0.165 |
 Birthweight in kg, mean (SD) | 3.01 (0.57) | 2.94 (0.62) | 3.07 (0.52) | 0.130 |
 Low birth weight < 2500 g, % (n) | 9.5 (15/158) | 7.7 (6/78) | 11.3 (9/80) | 0.410 |
 IPTp-SP doses, median (IQR) | 3 (2–4) | 3 (2–4) | 3 (2–3) | 0.627 |