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Table 1 SETBP1 mutations in chronic myelomonocytic leukemia

From: SETBP1 mutations as a biomarker for myelodysplasia /myeloproliferative neoplasm overlap syndrome

Reference Number of Patients Mutation Prevalence Impact on Survival
[38] 195 12 (6.2%) Yes (p-0.028)
[39] 179 8 (4.5%) Yes (p = 0.01)
[32] 294 21 (7.1%) No (p-0.798)
[31] 152 22 (14.5%) Yes (p-NR for CMML cohort)
[33] 466 21 (5%) No (p-0.07)
[40] 145 26 (18%) No (p-NR)
[45] 214 – Learning 260 – Validation 19 (8.9%) – Learning 24 (9.2%) – Validation Yes (p-0.04)
[43]* 1364 NR Yes (p < 0.001)
  1. NR Not reported; * Meta-analysis