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Table 1 Demographics and biomarker results of the study cohort

From: Re-evaluation of soluble APP-α and APP-β in cerebrospinal fluid as potential biomarkers for early diagnosis of dementia disorders

 

Number of subjects

Age

Gender

sAPPα

sAPPβ

p-tau

Aβ42

Groups

Total

NCNP

TMGH

TMNH

 

(M/F)

(ng/ml)

(ng/ml)

(pg/ml)

(pg/ml)

AD

33

21

3

9

75.5 ± 1.5

15/18

320.6 ± 22.6

594.9 ± 39.7

89.1 ± 5.8

677.8 ± 34.0

MCI-AD

17

7

7

3

70.6 ± 2.1

7/10

468.0 ± 66.4

785.4 ± 101.2

91.7 ± 9.5

562.0 ± 60.8

Non-AD

27

18

3

6

72.6 ± 1.6

14/13

235.5 ± 24.9

417.6 ± 33.6

43.9 ± 3.8

844.3 ± 55.2

Dis. control

19

16

0

3

67.5 ± 1.9

12/7

222.8 ± 25.0

383.6 ± 34.3

36.1 ± 2.7

1013.0 ± 71.2

  1. Data of statistical analyses are described in Fig. 3 and the text