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Table 1 Demographics and biomarker results of the study cohort

From: Re-evaluation of soluble APP-α and APP-β in cerebrospinal fluid as potential biomarkers for early diagnosis of dementia disorders

  Number of subjects Age Gender sAPPα sAPPβ p-tau Aβ42
Groups Total NCNP TMGH TMNH   (M/F) (ng/ml) (ng/ml) (pg/ml) (pg/ml)
AD 33 21 3 9 75.5 ± 1.5 15/18 320.6 ± 22.6 594.9 ± 39.7 89.1 ± 5.8 677.8 ± 34.0
MCI-AD 17 7 7 3 70.6 ± 2.1 7/10 468.0 ± 66.4 785.4 ± 101.2 91.7 ± 9.5 562.0 ± 60.8
Non-AD 27 18 3 6 72.6 ± 1.6 14/13 235.5 ± 24.9 417.6 ± 33.6 43.9 ± 3.8 844.3 ± 55.2
Dis. control 19 16 0 3 67.5 ± 1.9 12/7 222.8 ± 25.0 383.6 ± 34.3 36.1 ± 2.7 1013.0 ± 71.2
  1. Data of statistical analyses are described in Fig. 3 and the text