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Table 1 Cases of adult B-ALL with hyperdiploidy, t(1;19)/der(19)t(1;19), and TCF3-PBX1 fusion confirmed by FISH and/or polymerase chain reaction (PCR)

From: A (1;19) translocation involving TCF3-PBX1 fusion within the context of a hyperdiploid karyotype in adult B-ALL: a case report and review of the literature

Case Age/Sex Karyotype Reference
1*** 22/F 47,XX,t(1;19),+8/46,XX,-19,+der(19)t(1;19) [2]
2* 51/M 47,XY,add(1)(p36),der(3)(t3;?)(q23;?),+7,t(14;18)(q32;q21),t(15;22)(q26;q21),der(19)t(1;19)(q23;p13)[26]/46,XY[14] [13]
3* 38/M 56,XY,+4,+5,+6,+7,+8,+10,?del(10)(q22q24),+16,+19,der(19)t(1;19)(q23;p13),+21,der(21)t(1;21)(q11;p11.1),+22,inc[4]/57,idem,+14[4]/56,idem,-Y,+14[4] [3]
4*** 23/F 51,XX,+X,+5,+8,add(7)(p?),der(19)t(1;19)(q23;p13),+21,+22[13]/52,XX,+X,+5,+8,add(7)(p?),der(19)t(1;19)(q23;p13),+21,+22,+mar[2] [14]
5** 21/M 48,XXY?c,t(1;19)(q23;p13),del(1)(p22),+mar[4]/47,XXY?c[9] [14]
6*** 44/F 53-54,XX,+1,t(1;19)(p23;q13),+8,+8,+8,+11,add(7)(q34),+20,+22,+mar[cp3].ish(PBX1x4)(TCF3x3)(PBX1 con TCF3 x2) This report
  1. Prognostic data were limited for these cases.
  2. *Reference does not provide further clinical/prognostic data about the malignancy.
  3. **Reference indicates that disease did not relapse.
  4. ***Reference indicates that disease relapsed.