Figure 3

The six subclones from the bone marrow sample taken from an ALL patient. BAC probes containing the TEL, AML1, PAX5, p16 or IKZF1 genes were labeled with SpectrumGreen, PF555 (red), PF590 (orange), HyPer5 (purple) or PF415 (blue), respectively. The mixed probes were hybridized with the bone marrow sample of an ALL patient. The results revealed that there were six subclones showing distinct combinations of the signal patterns for the five selected genes. The details of the molecular profiling are shown in Table 3.