Table 3 Cox regression of overall survival, forced entry method
Covariates | N | HR | 95% CI | p |
|---|---|---|---|---|
Age | 1.022 | 1.002-1.042 | 0.033 | |
Risk group | ||||
Low risk | 32 | 1 | ||
Intermediate risk | 87 | 2.980 | 1.495-5.942 | 0.002 |
High risk | 55 | 5.993 | 2.912-12.333 | <0.001 |
Treatment | ||||
Chemotherapy | 118 | 1 | ||
Chemotherapy + allo-SCT | 56 | 0.231 | 0.118-0.450 | <0.001 |
IDH1 codon 132 | ||||
Wild type | 162 | 1 | ||
Mutated | 12 | 0.816 | 0.390-1.708 | 0.59 |
IDH2 codon 140 | ||||
Wild type | 155 | 1 | ||
Mutated | 19 | 1.942 | 1.068-3.530 | 0.030 |
IDH2 codon 172 | ||||
Wild type | 169 | 1 | ||
Mutated | 5 | 0.222 | 0.067-0.738 | 0.014 |
IDH1 SNP codon 105 GGC > GGT | ||||
Wild type | 154 | 1 | ||
Variant | 20 | 1.496 | 0.812-2.756 | 0.196 |