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Table 3 Cox regression of overall survival, forced entry method

From: Mutations in the isocitrate dehydrogenase 2 gene and IDH1 SNP 105C > T have a prognostic value in acute myeloid leukemia

Covariates N HR 95% CI p
Age   1.022 1.002-1.042 0.033
Risk group     
Low risk 32 1   
Intermediate risk 87 2.980 1.495-5.942 0.002
High risk 55 5.993 2.912-12.333 <0.001
Treatment     
Chemotherapy 118 1   
Chemotherapy + allo-SCT 56 0.231 0.118-0.450 <0.001
IDH1 codon 132     
Wild type 162 1   
Mutated 12 0.816 0.390-1.708 0.59
IDH2 codon 140     
Wild type 155 1   
Mutated 19 1.942 1.068-3.530 0.030
IDH2 codon 172     
Wild type 169 1   
Mutated 5 0.222 0.067-0.738 0.014
IDH1 SNP codon 105 GGC > GGT     
Wild type 154 1   
Variant 20 1.496 0.812-2.756 0.196
  1. 95% CI = 95% Confidence interval; HR = Hazard ratio.
  2. Significant P-values (P <0.05) in boldface.