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Table 1 LDCT in lung cancer screening

From: Lung cancer screening: from imaging to biomarker

Trial Name

Study design

No. recruited

Characteristics of participants

Exsmoker quit (yrs)

Year started

Report date

LC baseline rate (LDCT)

Stage I Cancer at Baseline

Age

Sex

Smoker(PkYr)

NLST [47]

LDCT vs CXR

53454

55–74

M/F

>=30

<15

2002

2011

1.0%

63.0%

NELSON [42, 95]

LDCT vs UC

15822

50–75

M/F

15–18.75

<10

2003

2016

0.9%

63.9%

ITALUNG [39]

LDCT vs UC

3206

55–69

M/F

>=20

<10

2004

NR

1.5%

47.6%

DEPISCAN [38]

LDCT vs CXR

765

50–75

M/F

>=15

<15

2002

2006

2.38%

0.9%

DANTE [37, 96]

LDCT vs UC

2472

60–74

M

>=20

<10

2001

2007

2.2%

57%

DLCST [97]

LDCT vs UC

4104

50–70

M/F

>=20

<10

2004

2016

0.8%

58.8%

LSS [34, 36]

LDCT vs CXR

3318

55–77

M/F

>=30

<10

2000

2005

1.9%

53.3%

  1. LDCT= low-dose computed tomography; CXR=chest X-ray; NC=usual care; M=male; F=female; PkYr=packs/year; yrs=years; f/u=follow-up; NR=not reported; LC=lung cancer.