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Table 1 Clinical characteristics of patients included into the study

From: MicroRNAs predict early complications of autologous hematopoietic stem cell transplantation

Variable

N = 77 (100%)

Disease

MM: 54 (70.1)

HL: 11 (14.3)

MCL: 5 (6.5)

DLBCL: 3 (3.9)

Other: 4 (5.2)

Conditioning regimen

Mel-200: 39 (50.6)

Reduced Mel: 16 (20.8)

BeEAM: 17 (22.1)

BEAM: 5 (6.5)

Variable

MM

ML

p

Sex

F: 29 (53.7)

M: 25 (46.3)

F: 11 (47.8)

M: 12 (52.2)

0.8233

Age at AHSCT

Median (25–75%), years

61.3 (53.8–66.4)

47.4 (39.5–54.1)

< 0.0001

Number of CD34 + cells transplanted (× 106 cells/kg)

Median (25–75%)

3.9 (3.1–5.3)

4.6 (3.3–5.7)

0.4092

Mucositis- any grade

34 (64.2)

23 (100.0)

0.0004

Mucositis– grade ≥ 2

18 (34.0)

22 (95.7)

< 0.0001

Bacteremia

11 (20.4)

8 (34.8)

0.2920

Neutropenic fever

30 (58.8)

18 (78.3)

0.1745

Days to PLT engraftment

Median (25–75%)

10 (10–13)

15 (12–18)

0.0001

Days to ANC engraftment

Median (25–75%)

11

10

0.0299

  1. ANC- absolute neutrophil count; BEAM- carmustine, etoposide, cytarabine, melphalan; BeEAM- bendamustine, etoposide, cytarabine, melphalan; DLBCL- diffuse large B-cell lymphoma; HL- Hodgkin Lymphoma; 25–75%- interquartile range; MCL- mantle cell lymphoma; MEL- melphalan; ML- malignant lymphoma; MM- multiple myeloma; PLT- platelets