Table 1 Clinicopathologic characteristics of patients
Variable | Analytic set | Â | Test set | ||
|---|---|---|---|---|---|
Control | SCLC | Â | Normal | SCLC | |
Patients, n | 5 | 5 | Â | 50 | 76 |
Age | 61.8 ± 5.3 | 59.2 ± 7.2 |  | 55.88 ± 9.7 | 64.2 ± 8.2 |
Male sex (%) | 5 (100.0) | 5 (100.0) | Â | 27 (54.0) | 67 (88.2) |
Smoking status | Â | Â | Â | Â | Â |
Never, n (%) | · | · |  | 28 (56.0) | 5 (6.6) |
Former/current, n(%) | 5 (100.0) | 5 (100.0) | Â | 22 (44.0) | 71 (93.4) |
Smoking amound, pack/year, mean ± SD | 30.14 ± 10.3 | 58 ± 27.7 |  | 14.16 ± 19.2 | 33.79 ± 19.0 |
Underlying comorbidities | 2 | 4 | Â | 29 | 50 |
Respiratory diseases, n(%) | · | 2 (40.0) |  | 2 (4.0) | 20 (26.3) |
Cardiovascular diseases, n(%) | 2 (40.0) | 4 (80.0) | Â | 22 (44.0) | 35 (46.0) |
Other medical conditions, n(%) | 1 (20.0) | 2 (40.0) | Â | 17 (34.0) | 17 (22.4) |
STAGE | Â | Â | Â | Â | Â |
Limited, n (%) | · | 5 (100.0) |  | · | 28 (36.8) |
Median OS (95% CI), months | · 30 (14.0 to 36.4) |  | · 25 (23.2 to 34.4) | ||
Extensive, n (%) | · | · |  | · | 48 (63.2) |
Median OS (95% CI), months | · | · |  | · 10 (9.9 to 15.6) | |
Tumor invasion | Â | Â | Â | Â | Â |
T1 + T2 | · | 2 (40.0) |  | · | 32 (42.1) |
T3 + T4 | · | 3 (60.0) |  | · | 44 (57.9) |
Lymph node metastasis | Â | Â | Â | Â | Â |
Negative | · | · |  | · | 11 (14.5) |
Positive | · | 5 (100.0) |  | · | 65 (85.5) |
Distant metastasis | Â | Â | Â | Â | Â |
Negative | · | 5 (100.0) |  | · | 32 (42.1) |
Positive | · | · |  | · | 44 (57.9) |
Treatment modality | Â | Â | Â | Â | Â |
CCRT | · | 4 (80.0) |  | · | 30 (39.5) |
Chemotherapy | · | 1 (20.0) |  | · | 46 (60.5) |
Surgery | Â | Â | Â | Â | Â |
Yes | · | · |  | · | · |
No | · | 5 (100.0) |  | · | 76 (100.0) |