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Table 3 Accuracy of plasma prorenin and PRA for detecting coronary artery disease

From: Higher plasma prorenin concentration plays a role in the development of coronary artery disease

 

Cutoff

Sensitivity

Specificity

PPV

NPV

Prorenin (pg/ml)

1,100

25 (15–34)

96 (92–100)

94 (88–99)

36 (25–46)

PRA (ng/ml/hr)

0.8

36 (26–46)

69 (59–79)

72 (63–81)

32 (22–42)

  1. The optimal cutoff values were determined by receiver-operating-characteristic curve analysis. Data are percentages. Numbers in parentheses are 95 % confidence intervals. PPV: positive predictive value, NPV: negative predictive value. PRA: plasma renin activity