Reference | Study group | No. of patients | CNS status | Treatment/Course/Outcome |
---|---|---|---|---|
[15] | DCLSG/POG | 10 | 5 | Treatment N/S |
6 died of leukemia | ||||
1 died of leukemia and infection | ||||
1 died of infection | ||||
1 died of treatment related toxicity | ||||
1 alive, 22Â months after BMT in CR1 | ||||
[13] | CCG | 2 | 2 | 1 relapsed in bone marrow with bilateral chloromas on the hips. Treated with radiation and BMT, but later died due to disease |
1 relapsed twice, treated with BMT, alive after 2Â years | ||||
[6] | DCOG | 6 | N/S | Treatment N/S |
Median EFS: 9Â months | ||||
3-year EFS: 0Â % | ||||
3-year OS: 0Â % | ||||
[19] | Japan | 1 | N/S | Alive after 5Â years, treated with chemotherapy only |
[16] | Korea | 3 | N/S | 1 received cord blood transplantation at 11Â months, relapsed 4Â months later, then died at 16Â months |
1 died during induction chemotherapy from multiple organ failure | ||||
1 achieved remission, but relapsed at 10Â months, and died at 16Â months | ||||
[56] | COG | 8 | N/S | Treatment N/S |
3-year EFS: 14Â % | ||||
3-year OS: 28Â % | ||||
2 of 7 evaluable patients are alive (1 after chemotherapy, 1 after BMT) (personal communication) |