Species | Subsets | Surface markers | % in MNC | Chemokine receptors | Functions |
---|---|---|---|---|---|
Human | Classical | CD14++CD16- | 80-95 | CCR2highCX3CR1low | Phagocytosis |
 | Intermediate | CD14++CD16+ | 2-11 | CCR2midCX3CR1highCCR5+ | Pro-inflammatory |
 | Non-classical | CD14+CD16++ | 2-8 | CCR2lowCX3CR1high | Patrolling |
Mouse | Ly6Chigh (Ly6C+) | CD11b+CD115+Ly6Chigh | 40-45 | CCR2highCX3CR1low | Phagocytosis & Pro-inflammatory |
 | Ly6Cmiddle (Ly6C+) | CD11b+CD115+Ly6Cmiddle | 5-32 | CCR2highCX3CR1low | Pro-inflammatory |
 | Ly6Clow (Ly6C-) | CD11b+CD115 +Ly6Clow | 26-50 | CCR2lowCX3CR1high | Patrolling; tissue repair |