Table 3 List of metabolic pathway databases
From: Metabolomic analyses for atherosclerosis, diabetes, and obesity
Link of the databases | Teams or specificity | Numbers of metabolites | Data included |
|---|---|---|---|
BioCyc ( http://humancyc.org/) | Pathway/Genome database | 371 pathways | Tier 1: metabolites, enzymes activators/inhibitors and cofactors; Tier 2 and Tier 3: computationally predicted pathways and gene codes. |
HumanCyc ( http://biocyc.org/) | Bioinformatics database | 28,783 genes | Metabolic pathways and the human genome |
KEGG ( http://www.genome.jp/kegg/) | Kyoto Encyclopedia of Genes and Genomes | 372 reference pathways, >15,000 compounds, 7,742 drugs and ~11,000 glycan structures | Metabolic pathways hyperlinked to metabolite and protein/enzyme information |
Metacyc ( http://metacyc.org/) | Data base of nonredundant, experimentally elucidated metabolic pathways | More than 1,100 pathways of more than 1,500 different organisms | Pathways of both primary and secondary metabolisms as well as associated compounds, enzymes, and genes |
Reactome ( http://www.reactome.org/) | A curated, peer-reviewed knowledge base of biological pathways | More than 2,700 proteins, 2,800 reactions and 860 pathways for humans | Metabolic pathways, protein trafficking and signal pathways |