Fig. 1
From: The role and metabolic adaptations of neutrophils in premetastatic niches
Different tumor-derived factors in recruiting neutrophils. Different types of tumor cells characteristically secrete a range of chemokines and inflammatory factors to promote neutrophil infiltration. CXCL: C-X-C motif chemokine ligand; MIP2 α: macrophage inflammatory protein-2 alpha; IL: interleukin; HMGB1: high-mobility group box 1; GM-CSF: granulocyte–macrophage colony-stimulating factor; G-CSF: granulocyte colony-stimulating factor; TNF- α: tumor necrosis factor-alpha; LTB4: leukotriene B4; GCP-2: granulocyte chemotactic protein-2