Table 3 Diagnostic accuracy of BFS
From: Circulating bone morphogenetic protein 8A is a novel biomarker to predict advanced liver fibrosis
BFS cutoff point | Accuracy | % | SN | SP | PPV | NPV | LR + | LR- |
|---|---|---|---|---|---|---|---|---|
≥ 0.10 | 54.1 | 82.4 | 97.0 | 26.9 | 45.7 | 93.9 | 1.3 | 0.1 |
≥ 0.20 | 62.4 | 71.8 | 93.9 | 42.3 | 50.8 | 91.7 | 1.6 | 0.1 |
≥ 0.30 | 70.6 | 51.8 | 78.8 | 65.4 | 59.1 | 82.9 | 2.3 | 0.3 |
≥ 0.40 | 76.5 | 43.5 | 75.8 | 76.9 | 67.6 | 83.3 | 3.3 | 0.3 |
≥ 0.46 | 78.8 | 36.5 | 69.7 | 84.6 | 74.2 | 81.5 | 4.5 | 0.4 |
≥ 0.50 | 77.6 | 35.3 | 66.7 | 84.6 | 73.3 | 80.0 | 4.3 | 0.4 |
≥ 0.60 | 72.9 | 25.9 | 48.5 | 88.5 | 72.7 | 73.0 | 4.2 | 0.6 |
≥ 0.70 | 70.6 | 14.1 | 30.3 | 96.2 | 83.3 | 68.5 | 8.0 | 0.7 |
≥ 0.80 | 65.9 | 9.4 | 18.2 | 96.2 | 75.0 | 64.9 | 4.8 | 0.9 |
≥ 0.90 | 62.3 | 1.2 | 3.0 | 100 | 100 | 61.9 | - | 1.0 |