Table 1 Characteristics of participants in this study
From: A blood-based composite panel that screens Alzheimer’s disease
Characteristic | Discovery | Validation | ||||
|---|---|---|---|---|---|---|
CN (n = 26) | MCI (n = 27) | AD (n = 26) | CN (n = 51) | MCI (n = 50) | AD (n = 53) | |
Age, mean(SD),y | 68.42(8.45) | 67.03(5.53) | 66.42(5.91) | 65.10(5.90) | 66.22(5.70) | 65.32(5.78) |
Female, No.(%) | 18(69.23) | 13(48.15) | 16(61.54) | 33(64.70) | 23(46.00) | 29(54.72) |
APOE ε4 positive, No. (%) | 4(15.38) | 12(44.44)* | 14(53.85)* | 6(11.76) | 20(40.00)* | 27(50.94)* |
MMSE score, mean (SD) | - | 23.67(1.94) | 14.88(5.19)☨ | - | 24.48(2.61) | 14.88(5.19)☨ |
MoCA score, mean (SD) | 27.85(0.88) | 19.33(1.84)* | 11.04(4.82)*☨ | 27.37(0.85) | 19.08(3.34)* | 9.58(5.80)*☨ |
Education, mean(SD),y | 14.65(2.94) | 10.07(3.86)* | 8.58(4.07)* | 13.65(2.57) | 11.18(3.57)* | 8.77(4.64)*☨ |