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Fig. 1 | Biomarker Research

Fig. 1

From: Elevated ZNF704 expression is associated with poor prognosis of uveal melanoma and promotes cancer cell growth by regulating AKT/mTOR signaling

Fig. 1

Identification of ZNF704 as a biomarker in UM. A Transcriptomics analysis of genes dys-regulated in UM tissues as compared to normal tissues. B The volvano plot showing analysis of DEGs based on metastasis status in TCGA cohort (FDR < 0.05, | log2(fold change)|> 1). C Heatmap of gene expression in two groups divided according to metastasis status. D Pan-cancer analysis indicating that multiple cancer types were associated with ZNF704 expression. E IHC staining of ZNF704 in tumor (top) and adjacent normal (bottom) tissues. F Distribution of ZNF704 expression levels in the TCGA corhort. The dotted line represented the median ZNF704 expression and divided the patients into low-expression and high-expression groups. G Percentage of deceased patients in the TCGA cohort as a function of ZNF704 expression level

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Biomarker Research

ISSN: 2050-7771

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