Fig. 2

A weighted combination of four TCRs was associated with the prognosis of patients with an EGFR mutation with NSCLC. A Overall survival (left) and disease-free survival (right) analysis of low- and high-risk patients based on the combination of four TCRs. The risk score was negatively related to survival benefit regardless of OS or DFS (P < 0.001; Hazard Ratio [HR] = 9.65, 95% confidence interval [CI]: 2.27 to 41.12) or DFS (P = 0.02; HR = 2.61, 95% CI: 1.13 to 6.03). B Survival analysis of patients with a low and high frequency of Vβ5-6Jβ2-7, Vβ28Jβ2-2, and Vβ7-3Jβ2-5 by Kaplan-Meier analysis; Vβ24-1Jβ2-1 was published in our previous studies. Local alignment was used to calculate the similarity of the base (left) and amino acid (middle) sequences of Vβ5-6Jβ2-7 (C), Vβ28Jβ2-2 (D), and Vβ7-3Jβ2-5 (E). The proportion of the top 5 non-conservative amino acid sequences in patients with a high frequency of TCRs is also shown (right)