Fig. 3From: Functions and mechanisms of lncRNA MALAT1 in cancer chemotherapy resistanceBiogenesis of MALAT1. The original MALAT1 is transcribed by RNA Pol II, and then cleaved by RNase P to form mature MALAT1 and a smaller RNA. The mature MALAT1 localizes to the nuclear speckles, while the smaller RNA is further processed into mascRNA by RNase Z and CCA-adding enzymes and transported into the cytoplasmBack to article page