Table 2 Disease characteristic with univariate analysis in FL3a cohorts

Age

1.005

0.99–1.01

0.27

1.03

1.01–1.05

0.001

Male

1.12

0.88–1.42

0.34

1.05

0.64–1.74

0.83

Rai stage III/IV

1.75

1.29–2.37

 < 0.01

1.76

0.91–3.40

0.09

B symptom

1.20

0.84–1.70

0.31

2.06

1.10–3.87

0.02

β2-MG > 2.7 mg/L

1.11

0.87–1.42

0.39

2.66

1.56–4.55

 < 0.001

Lymph nodes > 4

1.36

1.05–1.77

0.02

1.35

0.78–2.32

0.27

Extranodal disease

1.22

0.93–1.60

0.14

1.02

0.56–1.86

0.93

Bulky disease

1.39

1.04–1.86

0.02

1.26

0.70–2.26

0.42

Marrow involved

1.45

1.07–1.97

0.01

1.82

1.00–3.29

0.047

HGB < 120 g/L

1.47

1.11–1.93

 < 0.01

1.53

1.12–1.64

 < 0.01

Spleen involved

0.74

0.53–1.03

0.07

1.40

0.81–2.43

0.22

LDH > 245U/L

1.50

1.17–1.92

0.001

5.53

3.19–9.58

 < 0.0001

LMR > 10

1.00

0.99–1.01

0.57

0.99

0.95–1.02

0.60

Ki-67 > 30%

0.82

0.56–1.21

0.33

0.79

0.33–1.87

0.60