Fig. 3

Comparison of clinical outcomes between patients with FL grade 1–2 and grade 3a stratified by FLIPI score. A-B Kaplan–Meier survival analysis of PFS A and OS B for FL1-2 and FL3a patients in FILPI low_risk group. 5-year PFS rate for FL1-2 patients with FLIPI 0–1(76.5%, range 0.71–0.83), in comparison with FL3a patients with FLIPI 0–1 (68.5%, range 0.61–0.78); stratified P > 0.05. 5-year OS rate for FL1-2 patients with FLIPI 0–1(95.4%, range 0.92–0.98), in comparison with FL3a patients with FLIPI 0–1 (94.0%, range 0.88–1.00); stratified P > 0.05. C-D Kaplan–Meier survival analysis of PFS C and OS D for FL1-2 and FL3a patients in FILPI intermediate_risk group. 5-year PFS rate for FL1-2 patients with FLIPI = 2 (66.3%, range 0.59–0.73), in comparison with FL3a patients with FLIPI = 2 (51.0%, range 0.41–0.62); stratified P = 0.001. 5-year OS rate for FL1-2 patients with FLIPI = 2 (90.4%, range 0.86–0.95), in comparison with FL3a patients with FLIPI = 2 (91.0%, range 0.83–0.99); stratified P > 0.05. E–F Kaplan–Meier survival analysis of PFS E and OS F for FL1-2 and FL3a patients in FILPI high_risk group. 5-year PFS rate for FL1-2 patients with FLIPI ≥ 3 (51.8%, range 0.43–0.61), in comparison with FL3a patients with FLIPI ≥ 3 (40.4%, range 0.31–0.51); stratified P < 0.05. 5-year OS rate for FL1-2 patients with FLIPI ≥ 3 (90.4%, range 0.84–0.96), in comparison with FL3a patients with FLIPI ≥ 3 (80.9%, range 0.72–0.89); stratified P > 0.05