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Fig. 3 | Biomarker Research

Fig. 3

From: Verification of prognostic expression biomarkers is improved by examining enriched leukemic blasts rather than mononuclear cells from acute myeloid leukemia patients

Fig. 3

Volcano plots showing transcripts associated with overall survival. Y-axis represents negative Log10 of observed P-values. X-axis represents log of the hazard ratio (HR). A. Figure shows results for OS in data from MNCs without any adjustment. B. Figure shows results for OS in data from VLBsCD34+ without any adjustment. C. Figure shows results for OS in data from MNCs after adjusting for gender (G), cytogenetic risk (C), and age (A). D. Figure shows results for OS in data from VLBsCD34+ after adjusting for gender (G), cytogenetic risk (C), and age (A). E. Figure shows results for OS in data from MNCs after adjusting for ELN risk (ELN) and age (A). F. Figure shows results for OS in data from VLBsCD34+ after adjusting for ELN risk (ELN) and age (A). Grey dots represent non-significant transcripts. Red dots represent significant transcripts with an increased expression associated with poor OS. Blue dots represent transcripts with a decreased expression associated with a poor OS.

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