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Fig. 2 | Biomarker Research

Fig. 2

From: The essential roles of FXR in diet and age influenced metabolic changes and liver disease development: a multi-omics study

Fig. 2

The effects of diets on hepatic metabolomes in WT and FXR KO mice. A Principal component analyses of liver metabolomes in WT and FXR KO mice B Venn diagrams show the numbers of distinct and overlapping metabolites that were changed by differential diet intake in 3 age groups (raw p value < 0.05 and FDR < 0.1). C Quantitative enrichment analyses of diet-altered metabolites. The top 10 pathways are shown (p value < 0.05). Common metabolic changes in metabolites and pathways found in both genotypes are marked in purple

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