The role and regulation of Maf proteins in cancer

Biomarker Research

Table 2 ncRNAs targeting Mafs in cancer

Cancer types	ncRNAs	Mafs	Functions of the interaction	Reference
Osteosarcoma	miR-4660	MafG	Inhibits Osteosarcoma cell growth	[70]
Lung adenocarcinoma	lncRNA MAFG-AS1	MafG	Suppresses the proliferation and induce apoptosis of lung adenocarcinoma cells	[71]
Lung adenocarcinoma	miR-7	MafG	Restores resistance to cisplatin	[72]
Prostate cancer	lncRNA EIF3J-AS1	MafG	Promotes proliferation and metastatic ability of prostate cancer cells	[73]
Oral cancer	LINC00284	MafG	Promotes cell proliferation and migration of oral squamous cell carcinoma	[74]
Laryngocarcinoma	miR-1290	c-Maf	Suppresses apoptosis of laryngeal squamous cell carcinoma cells	[75]
Neurofibroma	miR-155	c-Maf	Promotes tumor growth in plexiform neurofibroma	[76]
Multiple myeloma	lncRNA ANGPTL1-3	c-Maf	Increases bortezomib sensitivity of multiple myeloma cells	[10]
Nasopharyngeal carcinoma	miR-223	MafB	Inhibits cell proliferation and migration of nasopharyngeal carcinoma	[77]
Liver cancer	circ-ITCH	MafF	Inhibits the proliferation and induces cell apoptosis of hepatocellular carcinoma	[78]
Liver cancer	cia-MAF	MafF	Impairs tumorigenesis, self-renewal and metastatic capacities in liver cancer	[79]

ISSN: 2050-7771