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Table 3 The genomic features that are associated with the largest number of deep radiomic features (DRFs). We only report the top five significant genomic features in each of the three categories (risk genes, gene signatures and KEGG pathways)

From: Radiogenomic association of deep MR imaging features with genomic profiles and clinical characteristics in breast cancer

Genomic features

No. of significant DRFs

Top 5 radiomic feature kernels (ordered)

Risk genes

 RP11-57H14.3

1118

13, 14, 15, 12, 16

 FIBP

1050

13, 14, 15, 10, 11

 ATP6AP1L

1038

13, 14, 16, 10, 15

 OVOL1

1019

13, 14, 10, 16, 11

 RP11-400F19.8

1017

13, 14, 16, 12, 15

Gene signatures

 EndoPredict

848

13, 14, 12, 15, 11

 Prosigna (rorS)

1395

13, 14, 12, 11, 10

KEGG pathways

 Fatty acid metabolism

1269

12, 10, 11, 13, 9

 Insulin signaling pathway

1243

13, 12, 11, 14, 10

 Phenylalanine metabolism

1217

12, 13, 10, 9, 11

 RNA degradation

1211

12, 13, 11, 14, 15

 Tyrosine metabolism

1205

12, 9, 10, 11, 13