Skip to main content
Fig. 5 | Biomarker Research

Fig. 5

From: Radiogenomic association of deep MR imaging features with genomic profiles and clinical characteristics in breast cancer

Fig. 5

The results of radiogenomic association analyses between the radiomic features (RFs) and the genomic features (GFs). a the association results of 288 breast cancer risk genes and 4,096 deep radiomic features. b the association results of the 6 breast gene signatures with 4,096 deep radiomic features (DRFs). c the association results of the 182 KEGG pathway activity scores with 4,096 DRFs. d the association results of 288 breast cancer risk genes and 36 conventional radiomic features (CRFs). The association of gene signatures and KEGG pathway activity scores are not shown here because no significant associations have been identified. For a-d, the X-axis is the RFs. The Y-axis is the GFs. Red ones are significant ones. e the top 30 that are significantly associated with the GFs. Rows are the top 30 DRFs that have genomic significance (ranked by the frequency of the associated GFs). The first column is the ID of DRFs. The next three columns are the number of significant associations between the given DRF and the three sets of GFs, respectively. The fifth column is the accumulated number of significant associations that the given DRF has. The last column is the kernel where the given DRF is. f 14 CRFs are significantly associated with the 8 risk genes. Rows are the 14 CRFs that have genomic significance (ranked by the frequency of the associated GFs). The first column is the names of the CRFs. The second column is the risk genes. The third column is the adjusted p-values of the association analyses

Back to article page