Covariate | Odds ratio | 95% CI | P value* | Percent of cases correctly classified | AUROCa (95% CI) |
---|---|---|---|---|---|
Model #1: Plasma PCT, ROC-defined threshold | – | 81% | 0.721 (0.677–0.762) | ||
Procalcitonin > 4.24 ng/mL | 2.58 | 1.57 to 4.25 | 0.0002 | – | – |
Age (years) | 1.02 | 1.01 to 1.03 | 0.0007 | – | – |
Pathogen genus, Streptococcus | 0.52 | 0.20 to 1.30 | 0.16 | – | – |
Pathogen genus, Staphylococcus | 1.59 | 0.91 to 2.78 | 0.10 | – | – |
Pathogen genus, Klebsiella | 1.92 | 0.81 to 4.54 | 0.14 | – | – |
Model #2: Plasma PCT quartiles (continuous) | – | 80% | 0.711 (0.669–0.754) | ||
Procalcitonin, quartiles (continuous) | 1.47 | 1.17 to 1.85 | 0.001 | – | – |
Age (years) | 1.02 | 1.01 to 1.03 | 0.0007 | – | – |
Pathogen genus, Streptococcus | 0.52 | 0.21 to 1.31 | 0.17 | – | – |
Pathogen genus, Staphylococcus | 1.55 | 0.89 to 2.70 | 0.12 | – | – |
Pathogen genus, Klebsiella | 1.93 | 0.82 to 4.55 | 0.13 | – | – |
Model #3: Plasma PCT, 4th vs. 1st to 3rd quartiles | – | 81% | 0.702 (0.658–0.744) | ||
Procalcitonin, 4th quartile | 2.12 | 1.26 to 3.54 | 0.004 | – | – |
Age (years) | 1.02 | 1.01 to 1.03 | 0.0004 | – | – |
Pathogen genus, Streptococcus | 0.49 | 0.20 to 1.24 | 0.13 | – | – |
Pathogen genus, Staphylococcus | 1.54 | 0.89 to 2.69 | 0.13 | – | – |
Pathogen genus, Klebsiella | 2.07 | 0.88 to 4.88 | 0.10 | – | – |
Model #4: Plasma PCT, 4th vs. 1st quartile | – | 80% | 0.723 (0.660–0.780) | ||
Procalcitonin, 4th quartile | 3.30 | 1.53 to 7.12 | 0.002 | – | – |
Age (years) | 1.01 | 1.00 to 1.02 | 0.08 | – | – |
Pathogen genus, Streptococcus | 0.47 | 0.13 to 1.72 | 0.25 | – | – |
Pathogen genus, Staphylococcus | 1.35 | 0.62 to 2.97 | 0.45 | – | – |
Pathogen genus, Klebsiella | 1.93 | 0.48 to 7.78 | 0.36 | – | – |