Fig. 7
From: Identification of cerebral spinal fluid protein biomarkers in Niemann-Pick disease, type C1
Correlation of NPC1 cerebrospinal fluid CCL18 levels with NPC1 clinical phenotype. There appeared to be a possible negative correlation (p = 0.0532, rho = -0.42) between CSF CCL18 levels and Age of Neurological Onset when evaluating the entire cohort (a); however, the negative correlation became readily apparent (p = 0.0016, rho = -0.65) when evaluating individuals with an age of neurological onset < 20 years (b). c) We did not observe a correlation between CSF CCL18 levels and the concurrent NPC Neurological Severity Score. d) we did observe a strong positive correlation (p = 0.0017, rho = 0.61) between CSF CCL18 levels and Annualized Severity Index Scores