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Fig. 3 | Biomarker Research

Fig. 3

From: Protein biomarkers in cervicovaginal lavages for detection of endometrial cancer

Fig. 3

Protein biomarkers in cervicovaginal lavages discriminate patients diagnosed with EC from patients with benign conditions. Cervicovaginal biomarkers discriminating low-grade endometrial endometrioid carcinoma (EEC) or other endometrial cancer (EC) subtypes from benign conditions were identified using the receiver operating characteristics (ROC) analysis. The area under the curve (AUC) was reported for each tested protein, including cytokines (A), chemokines (B), growth factors (C), apoptosis-related proteins (D), hormones (E), tumor markers (F), and immune checkpoint proteins (G). The strength of the discriminators was measured with AUC values. Proteins with AUC greater than or equal to 0.8 or 0.9 (indicated in pink or purple) were considered as good or excellent discriminators, respectively

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