Fig. 4

The function of ovarian cancer cells by regulating PTBP3. a After knocking down PTBP3, the proliferation rate of EOC cells was slowed down within 96 hours. Data are mean ± SD from three independent replicate experiments. ***P<0.001. b Increased apoptosis of EOC cells after knockdown of PTBP3. Error bars represent the mean ± SD of three independent replicates. c The percentage of cells in G2 phase decreased after knockdown of PTBP3 (n=3). d The migration and invasion rates of ovarian cancer cells were decreased after knockdown of PTBP3 (n=3). e The proliferation of ovarian cancer cells was significantly accelerated after overexpression of PTBP3. **P<0.01. f Overexpression of PTBP3 significantly reduced apoptosis. Error bars represent the mean ± SD of three independent replicates. ***P<0.001, **P<0.01.g The percentage of EOC cells in G2 phase was significantly increased after overexpression of PTBP3 (n=3). h The migration and invasion of ovarian cancer cells were significantly increased after overexpression of PTBP3, data represent mean ± SD. **P<0.01