Fig. 4
Univariate Cox regression of prognostic mutated genes (A). Bar graph shows 9 prognostic mutated genes ordered by their univariate z-score for overall survival. A positive score indicates nonsynonymous mutations in the genes are associated with shorter survival, and negative scores are associated with longer survival. The dashed line (colored in red) represents an absolute univariate z-score value of ± 1.96. ROC curve analysis of overall survival prediction by the 9-mutational gene signature in patients with EAC (B)