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Fig. 5 | Biomarker Research

Fig. 5

From: Development of a novel BRCAness score that predicts response to PARP inhibitors

Fig. 5

The association of the BRCAness score with BRCA mutation in breast cancer cell lines. A Bar plots of BRCAness score by 37 breast cancer cell lines in CCLE data base. Orange, green, and blue bars show BRCA1-mutation, BRCA2-mutation, and wildtype, respectively. B Boxplots of BRCAness score by different cells, including stromal cells, myeloid cells, B cells, T cells, and cancer cells, in bulk tumor in GSE75688 cohort. P-values were calculated by the Kruskal-Wallis test

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