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Fig. 2 | Biomarker Research

Fig. 2

From: Loss of miR-637 promotes cancer cell stemness via WASH/IL-8 pathway and serves as a novel prognostic marker in esophageal squamous cell carcinoma

Fig. 2

miR-637 suppresses stem-like characteristics in ESCC cells by inhibiting IL-8 expression. A, B qRT-PCR (A) and ELISA (B) assays showed the expression levels of IL-8 in KYSE70 cells and KYSE450 cells after treatment with negative control (NC) mimic or miR-637 mimic. C, D qRT-PCR (C) and ELISA (D) assays showed the expression levels of IL-8 in KYSE70 cells and KYSE450 cells after treatment with NC inhibitor or miR-637 inhibitor. E, F The number of spheres derived from KYSE70 cells and KYSE450 cells after treatment with treated with miR-637 mimic (E) or miR-637 inhibitor (F). G The number of spheres derived from IL-8 overexpressing (OE-IL-8) KYSE450 cells after treatment with miR-637 mimic. Scale bar, 200 μm. Data are presented as mean ± standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001

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Biomarker Research

ISSN: 2050-7771

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