Fig. 4From: SGOL2 is a novel prognostic marker and fosters disease progression via a MAD2-mediated pathway in hepatocellular carcinomaOverexpression of MAD2 reversed the knockdown effects of SGOL2-shRNA in HCC. A-D, F Invasion, migration, sphere formation, and colony formation assays of SGOL2 knockdown HCC cells with or without MAD2 overexpression were performed. E SK-HEP-1, and HEP3B cells were transfected with shSGOL2 or MAD2 plasmid, and the proliferation of HCC cells was detected at Days 3 by CCK-8 assays. The results are presented as the mean ± SD, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001Back to article page