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Fig. 1 | Biomarker Research

Fig. 1

From: The pivotal application of patient-derived organoid biobanks for personalized treatment of gastrointestinal cancers

Fig. 1

The flow chart of the establishment of living biobanks of GIC PDOs and the application of GIC PDOs in personalized treatment. Notes: PDOs of GICs can be cryopreserved and stored in the living organoid biobanks for cancer research. PDOs of GICs recapitulate their morphology, pathology, and, genetic traits of the original tumors (upper panel). The PDO technology has the application of personalized treatment allowing for chemotherapy, radiotherapy, targeted therapy, immunotherapy, or the combination of their selections for an individual patient with GICs (lower panel). PDOs-Patient-derived organoids. GIC-Gastrointestinal cancer

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