Fig. 7From: CAR-T cell potency: from structural elements to vector backbone componentsA schematic picture of the LTR and also termination signals present within the U3 region. Studies showed that besides USE, two additional elements in U3, the transcriptional control region and the nuclear factor of activated T cells/upstream stimulatory factor (NFAT/USF) binding region, contribute significantly to lentiviral LTR transcriptional terminationBack to article page