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Fig. 6 | Biomarker Research

Fig. 6

From: Long noncoding RNA HOXC-AS3 interacts with CDK2 to promote proliferation in hepatocellular carcinoma

Fig. 6

HOXC-AS3 functions through CDK2. A Colony formation assays with oe-vec, oe-HOXC-AS3, oe-HOXC-AS3 + siNC and oe-HOXC-AS3 + siCDK2 groups in Hep3B cells. B CCK-8 assays with oe-vec, oe-HOXC-AS3, oe-HOXC-AS3 + siNC and oe-HOXC-AS3 + siCDK2 groups in Hep3B cells. C EdU assays with oe-vec, oe-HOXC-AS3, oe-HOXC-AS3 + siNC and oe-HOXC-AS3 + siCDK2 groups in Hep3B cells. D Cell cycle assays analysis with oe-vec, oe-HOXC-AS3, oe-HOXC-AS3 + siNC and oe-HOXC-AS3 + siCDK2 groups in Hep3B cells. E Colony formation assays with siNC, Aso-HOXC-AS3, Aso-HOXC-AS3 + pcDNA-vec and Aso-HOXC-AS3 + pcDNA-CDK2 groups in HLF cells. F CCK-8 assays with siNC, Aso-HOXC-AS3, Aso-HOXC-AS3 + pcDNA-vec and Aso-HOXC-AS3 + pcDNA-CDK2 groups in HLF cells. G EdU assays with siNC, Aso-HOXC-AS3, Aso-HOXC-AS3 + pcDNA-vec and Aso-HOXC-AS3 + pcDNA-CDK2 groups in HLF cells. H Cell cycle assays analysis with siNC, Aso-HOXC-AS3, Aso-HOXC-AS3 + pcDNA-vec and Aso-HOXC-AS3 + pcDNA-CDK2 groups in HLF cells. Data represent the MEAN ± S.E.M of three independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001 (Student’s t test)

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