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Fig. 8 | Biomarker Research

Fig. 8

From: CircRNA 0009043 suppresses non-small-cell lung cancer development via targeting the miR-148a-3p/DNAJB4 axis

Fig. 8

DNAJB4 Reversed the Regulatory Effect of miR-148a-3p on A549 and HCC827 cells. A549 and HCC827 cells were transfected with shCirc, shCirc + miR-148a-3p inhibitor negative control (Inhibitor NC), shCirc + miR-148a-3p inhibitor (Inhibitor), shCirc + miR-148a-3p inhibitor (Inhibitor) + shCTRL, or shCirc + miR-148a-3p inhibitor + shDNAJB4, respectively. A Viability in A549 and HCC827 cells at 0, 24, and 48 h. B EdU assay to detect A549 and HCC827 cell proliferation ability. C FSCS assay to detect A549 and HCC827 cell apoptosis. D Protein levels of E-cadherin, N-cadherin, Vimentin and Slug in A549 and HCC827 cells with the indicated transfection were determined by western blot. GAPDH is a loading control. Data are presented as mean ± standard deviation. **P < 0.01; *** P < 0.001

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