Table 3 Characteristics of participants in dataset 3
From: A circular RNA blood panel that differentiates Alzheimer’s disease from other dementia types
Characteristic | Total Sample (n = 321) | Controls (n = 58) | AD (n = 60) | VaD (n = 50) | PDD (n = 51) | bvFTD (n = 52) | DLB (n = 50) |
|---|---|---|---|---|---|---|---|
Age, mean (SD) | 68.6 (6.7) | 68.8 (7.5) | 67.6 (6.8) | 69.5 (5.9) | 69.6 (7.3) | 67.8 (6.9) | 68.4 (5.6) |
Education year, mean (SD) | 9.4 (2.2) | 9.1 (1.8) | 9.1 (2.2) | 9.2 (2.2) | 9.4 (2.4) | 9.6 (2.2) | 10.1 (2.3) |
Women, No. (%) | 165 (51.4) | 29 (50.0) | 31 (51.7) | 26 (52.0) | 26 (51.0) | 27 (51.9) | 26 (52.0) |
ApoE ε4 positive (%) | 77 (24.0) | 10 (17.2) | 25 (41.7)* | 12 (24.0) | 10 (19.6) | 10 (19.2) | 10 (20) |
MMSE score, mean (SD) | 22 (4.2) | 29.1 (0.6) | 19.6 (2.6)* | 19.9 (2.8)* | 21.4 (2.6)* | 19.7 (2.7)* | 21.6 (2.9)* |
Aβ42, mean (SD), pg/ml | 631.7 (193) | 703.8 (123.5) | 346.6 (81.6)* | 713.5 (123.6) | 741.6 (162.4) | 706.3 (125.4) | 655.1 (120.4) |
T-tau, mean (SD), pg/ml | 423.8 (148.1) | 343.9 (136.9) | 596.2 (145.8)* | 412.2 (102.6) | 369.9 (100.9) | 409.9 (110.9) | 390.6 (116.8) |
P-tau, mean (SD), pg/ml | 59.2 (33.5) | 52 (23.4) | 104.6 (49)* | 46.9 (12.9) | 50.3 (15.4) | 48.2 (11) | 46 (12) |