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Table 3 Characteristics of participants in dataset 3

From: A circular RNA blood panel that differentiates Alzheimer’s disease from other dementia types

Characteristic Total Sample (n = 321) Controls (n = 58) AD (n = 60) VaD (n = 50) PDD (n = 51) bvFTD (n = 52) DLB (n = 50)
Age, mean (SD) 68.6 (6.7) 68.8 (7.5) 67.6 (6.8) 69.5 (5.9) 69.6 (7.3) 67.8 (6.9) 68.4 (5.6)
Education year, mean (SD) 9.4 (2.2) 9.1 (1.8) 9.1 (2.2) 9.2 (2.2) 9.4 (2.4) 9.6 (2.2) 10.1 (2.3)
Women, No. (%) 165 (51.4) 29 (50.0) 31 (51.7) 26 (52.0) 26 (51.0) 27 (51.9) 26 (52.0)
ApoE ε4 positive (%) 77 (24.0) 10 (17.2) 25 (41.7)* 12 (24.0) 10 (19.6) 10 (19.2) 10 (20)
MMSE score, mean (SD) 22 (4.2) 29.1 (0.6) 19.6 (2.6)* 19.9 (2.8)* 21.4 (2.6)* 19.7 (2.7)* 21.6 (2.9)*
Aβ42, mean (SD), pg/ml 631.7 (193) 703.8 (123.5) 346.6 (81.6)* 713.5 (123.6) 741.6 (162.4) 706.3 (125.4) 655.1 (120.4)
T-tau, mean (SD), pg/ml 423.8 (148.1) 343.9 (136.9) 596.2 (145.8)* 412.2 (102.6) 369.9 (100.9) 409.9 (110.9) 390.6 (116.8)
P-tau, mean (SD), pg/ml 59.2 (33.5) 52 (23.4) 104.6 (49)* 46.9 (12.9) 50.3 (15.4) 48.2 (11) 46 (12)
  1. The values of age, education year, MMSE, Aβ42, T-tau, and P-tau are shown as mean (SD)
  2. Abbreviations: AD Alzheimer’s disease, VaD vascular dementia, PDD Parkinson disease dementia, bvFTD behavioral variant frontotemporal dementia, DLB dementia with Lewy body, ApoE ε4 apolipoprotein ε4, MMSE Mini-Mental State Examination, SD standard deviation
  3. *P < 0.05 compared to controls