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Fig. 2 | Biomarker Research

Fig. 2

From: Detection of circulating tumor cells: opportunities and challenges

Fig. 2

Outline of existing isolation techniques. The majority of CTC enrichment methods utilize the unique surficial antigen expression of CTCs or the physical or functional property of CTCs to separate CTCs from the great number of erythrocytes, leukocytes, and other blood. EpCAM: epithelial cell adhesion molecule; RBC: red blood cell; WBC: white blood cell; CTC: circulating tumor cell; GFP: green fluorescent protein; hTERT: human telomerase reverse transcriptase; SPPCNs: superparamagnetic positively charged nanoparticles

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